[1]Bilezikjian L M,Blount A L,Donaldson C J,et al. Pituitary actions of ligands of the TGF-β family:activins and inhibins[J]. Reproduction,2006,132:207-215.
[2]Massagué J. TGF-beta signal transduction[J]. Annual Review of Biochemistry,1998,67:753-791.
[3]Bilezikjian L M,Blount A L,Leal A M O,et al. Autocrine/paracrine regulation of pituitary function by activin,inhibin and follistatin[J]. Molecular and Cellular Endocrinology,2004,225(1/2):29-36.
[4]Thompson T B,Woodruff T K,Jardetzky T S. Structures of an ActRⅡB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions[J]. The EMBO Journal,2003,22(7):1555-1566.
[5]Harrington A E,Morris-Triggs S A,Ruotolo B T,et al. Structural basis for the inhibition of activin signalling by follistatin[J]. The EMBO Journal,2006,25(5):1035-1045.
[6]Keller S,Nickel J,Zhang J L,et al. Molecular recognition of BMP-2 and BMP receptor IA[J]. Nature Structural & Molecular Biology,2004,11(5):481-488.
[7]Greenwald J,Groppe J,Gray P,et al. The BMP7/ActRⅡ extracellular domain complex provides new insights into the cooperative nature of receptor assembly[J]. Molecular Cell,2003,11(3):605-617.
[8]Brown M A,Zhao Qinghai,Baker K A,et al. Crystal structure of BMP-9 and functional interactions with pro-region and receptors[J]. The Journal of Biological Chemistry,2005,280(26):25111-25118.
[9]Rost B. Predicting one-dimensional protein structure by profile based neural networks[J]. Methods in Enzymology,1996,266:525-39.
[10]Wu S,Skolnick J,Zhang Y. Ab initio modeling of small proteins by iterative TASSER simulations[J]. BMC Biology,2007,5:17.
[11]Mathews L S,Vale W W. Expression cloning of an activin receptor,a predicted transmembrane serine kinase[J]. Cell,1991,65(6):973-982.
[12]Harrison C A,Gray P C,Vale W W,et al. Antagonists of activin signaling:mechanisms and potential biological applications[J]. Trends in Endocrinology & Metabolism,2005,16(2):73-78.
[13]Wiater E,Vale W. Inhibin is an antagonist of bone morphogenetic protein signaling[J]. The Journal of Biological Chemistry,2003,278(10):7934-7941.
[14]Rengachary S S. Bone morphogenetic proteins:basic concepts[J]. Neurosurgical Focus,2002,13(6):1-6.
[15]Mathews L S,Vale W W,Kintner C R. Cloning of a second type of activin receptor and functional characterization in Xenopus embryos[J]. Science,1992,255(552):1702-1705.
[16]Gray P C,Greenwald J,Blount A L,et al. Identification of a binding site on the type Ⅱ activin receptor for activin and inhibin[J]. The Journal of Biological Chemistry,2000,275(5):3206-3212.
[17]Lewis K A,Gray P C,Blount A L,et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling[J]. Nature,2000,404(6776):411-414.
[18]MacConell L A,Leal A M O,Vale W W. The distribution of betaglycan protein and mRNA in rat brain,pituitary,and gonads:implications for a role for betaglycan in inhibin-mediated reproductive functions[J]. Endocrinology,2002,143(3):1066-1075.
[19]Chapman S C,Woodruff T K. Betaglycan localization in the female rat pituitary:implications for the regulation of follicle-stimulating hormone by inhibin[J]. Endocrinology,2003,144(12):5640-5649.
[20]Wiater E,Harrison C A,Lewis K A,et al. Identification of distinct inhibin and transforming growth factorβ-binding sites on betaglycan[J]. The Journal of Biological Chemistry,2006,281(25):17011-17022.
[21]Makanji Y,Walton K L,Wilce M C,et al. Suppression of inhbin A biological activity by alterations in the binding site for betaglycan[J]. The Journal of Biological Chemistry,2008,283(24):16743-16751.