|本期目录/Table of Contents|

[1]赖家豪,熊桂红,刘冰,等.放线菌活性物质的挖掘与分离技术研究进展[J].江苏农业科学,2022,50(13):82-89.
 Lai Jiahao,et al.Research progress on mining and separation technology of active substances from actinomycete[J].Jiangsu Agricultural Sciences,2022,50(13):82-89.
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放线菌活性物质的挖掘与分离技术研究进展(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第50卷
期数:
2022年第13期
页码:
82-89
栏目:
专论与综述
出版日期:
2022-07-05

文章信息/Info

Title:
Research progress on mining and separation technology of active substances from actinomycete
作者:
赖家豪 熊桂红 刘冰 蒋军喜 游婧 刘彤珂
江西农业大学农学院植物保护系,江西南昌 330045
Author(s):
Lai Jiahaoet al
关键词:
放线菌活性物质挖掘分离技术基因组挖掘微生物资源
Keywords:
-
分类号:
S182
DOI:
-
文献标志码:
A
摘要:
放线菌是一类广泛分布且备受人类关注的微生物资源,其能产生多种多样的结构新颖、具有生物活性的次级代谢产物,是多种天然产物的重要来源,具有极大的研究和开发价值。本文阐述了以生物活性为导向进行筛选挖掘、基因组挖掘、转录组挖掘等放线菌天然活性物质的挖掘手段,并结合近年研究成果分别论证各方法的优势及适用条件,为合理选择挖掘手段提供参考;概述了溶媒萃取法、离子交换层析法、薄层层析法等天然活性物质分离方法及其优缺点。文中重点综述伴随着基因组学和现代分子生物学的迅速发展而兴起的包括生物信息学分析、同源表达、异源表达等利用基因组挖掘活性物质的方法,以期为微生物资源的挖掘与利用提供相应的参考。最后合理分析目前放线菌开发利用中存在的一些问题,并简要提出相应的建议,就将来放线菌的研究方向和发展前景进行了展望。
Abstract:
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备注/Memo

备注/Memo:
收稿日期:2021-11-05
基金项目:国家自然科学基金(编号:31460139);江西省自然科学基金(编号:20161BAB204184);江西省科技支撑计划(编号:20121BBF60024)。
作者简介:赖家豪(1998—),男,江西瑞金人,硕士,主要从事植物病理学研究。E-mail:2286349575@qq.com。
通信作者:刘冰,博士,副教授,主要从事植物病害生物防治方面的研究。E-mail:lbzjm0418@126.com。
更新日期/Last Update: 2022-07-05