|本期目录/Table of Contents|

[1]胡永红,曹峥,杨文革,等.多效霉素研究进展[J].江苏农业科学,2013,41(12):1-4.
 Hu Yonghong,et al.Research progress of polyoxin[J].Jiangsu Agricultural Sciences,2013,41(12):1-4.
点击复制

多效霉素研究进展(PDF)
分享到:

《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第41卷
期数:
2013年12期
页码:
1-4
栏目:
专论
出版日期:
2013-12-25

文章信息/Info

Title:
Research progress of polyoxin
作者:
胡永红 曹峥 杨文革 李佼佼 开玉美 梁萌萌
南京工业大学,江苏南京 211816
Author(s):
Hu Yonghonget al
关键词:
多效霉素生物农药作用机理生物合成
Keywords:
-
分类号:
A
DOI:
-
文献标志码:
S482.2+8
摘要:
多效霉素是一种抗真菌核苷类抗生素,能够抑制真菌细胞壁几丁质的合成,并且对农作物、鱼和哺乳动物安全。目前生产的多效霉素大部分都是可可链霉菌阿苏变种发酵产生的。就多效霉素的作用机理、生物合成、化学合成和应用及市场等方面进行了研究,并对其发展进行了展望。
Abstract:
-

参考文献/References:

[1]Isono K,Asahi K,polyoxins S O,et al. 13.The structure of polyoxins[J]. Journal of the American Chemical Society,1969,91(26):7490-7505.
[2]Isono K,Nagatsu J,Kawashima Y,et al. Studies on polyoxins,antifungal antibiotics.Ⅰ.Isolation and characterization of polyoxins A and B[J]. Agricultural and Biological Chemistry,1965,29:848-854.
[3]Merzendorfer H,Zimoch L. Chitin metabolism in insects:structure,function and regulation of chitin synthases and chitinases[J]. Journal of Experimental Biology,2003,206(24):4393-4412.
[4]Shiro Y,Kato K,Fujii M,et al. First synthesis of polyoxin M[J]. Tetrahedron,2006,62(37):8687-8695.
[5]吴家全,李军民. 多抗霉素研究现状与市场前景[J]. 农药科学与管理,2010,31(11):21-23.
[6]Isono K,Nagatsu J,Kawashima Y,et al. Studies on polyoxins,antifungal antibiotics[J]. Arg Biol Chem,1965,29(9):848-854.
[7]Casiraghi G,Zanardi F,Rassu G,et al. Stereoselective approaches to bioactive carbohydrates and alkaloids-with a focus on recent syntheses drawing from the chiral pool[J]. Chemical Reviews,1995,95(6):1677-1716.
[8]Mueller H,Furter R,Zaehner H,et al. Metabolic products[yeasts]of microorganisms,203:Inhibition of chitosomal chitin synthetase and growth of Mucor rouxii by nikkomycin Z,nikkomycin X,and polyoxin A:A comparison[J]. Archives of Microbiology,1981,130(3):195-197.
[9]于福利,宋喜峰,姜军侠,等. 多效霉素B的高效液相色谱分析方法[J]. 农药,2008(47):188-189.
[10]钟建江,孙力. 多氧霉素B的定量分析检测方法:中国,101302558[P]. 2008-6-26.
[11]Sun L,Chen W Q,Deng Z X,et al. Microbiological assay for quantitative determination of polyoxin B[J]. Process Biochemistry,2009(44):361-364.
[12]陈西广,刘万顺,刘晨光.几丁质的研究与进展[J]. 生物工程进展,1997,17(3):4-8.
[13]Gooday G W. The action of polyoxin on fungi[M]. Berlin:Akademie-Verlag,1979:159-168.
[14]Cablb E. Molecular aspects of yeast morphogenesis[J]. Annual Review of Microbiology,1975,29:191-214.
[15]Endo A,Misato T. Polyoxin D,a competitive inhibitor of UDP-N-acetylglucosamine:chitin N-acetylglucosaminyltransferase in Neurospora crassa[J]. Biochemical and Biophysical Research Communications,1969,37(4):718-722.
[16]Kunitoyo S,Michio T,Takeo N,et al. Transformation of polyoxins D,E and F with Sodium bisulfite[J]. Biological Chemistry,1972,36(7):1229-1236.
[17]Isono K,Asahi K,Suzuki S. Polyoxins,antifungal antibiotics. ⅩⅢ. Structure of polyoxins[J]. Journal of the American Chemical Society,1969,91(26):7490-7505.
[18]Li J,Li L,Feng C,et al. Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes[J]. Microbial Cell Factories,2012,11:135.
[19]Zhao C,Huang T,Chen W,et al. Enhancement of the diversity of polyoxins by a thymine-7-hydroxylase homolog outside the polyoxin biosynthesis gene cluster[J]. Applied and Environmental Microbiology,2010,76(21):7343-7347.
[20]Ohta,N,Kakiki,et al. Studies on the mode of action of polyoxin D.Ⅱ.Effect of polyoxin D on the synthesis of fungal cell wall chitin[J]. Agricultural and Biological Chemistry,1970(34):1224-1234.
[21]Misato T,Kakiki K,Hori M. Mechanism of polyoxin resistance[J]. Netherlands Journal of Plant Pathology,1977(83):253-260.
[22]叶丽娟,朱辉,田敏. 微生物来源的真菌细胞壁抑制剂的研究进展[J]. 国外医药抗生素分册,2005,26(1):34-41.
[23]Zhang D,Miller M J. Polyoxins and nikkomycins:progress in synthetic and biological studies[J]. Current Pharmaceutical Design,1999,5(2):73-99.
[24]Naider F,Shenbagamurthi P,Steinfeld A S,et al. Synthesis and biological activity of tripeptidyl polyoxins as antifungal agents[J]. Antimicrobial Agents and Chemotherapy,1983,24(5):787-796.
[25]Shenbagamurthi P,Smith H A,Becker J M,et al. Design of anticandidal agents:synthesis and biological properties of analogues of polyoxin L[J]. Journal of Medicinal Chemistry,1983,26(10):1518-1522.
[26]Khare R K,Becker J M,Naider F R. Synthesis and anticandidal properties of polyoxin L analogues containing alpha-amino fatty acids[J]. Journal of Medicinal Chemistry,1988,31(3):650-656.
[27]Emmer G,Ryder N S,Grassberger M A. Synthesis of new polyoxin derivatives and their activity against chitin synthase from Candida albicans[J]. Journal of Medicinal Chemistry,1985,28(3):278-281.
[28]Delzer J,Fiedler H P,Müller H,et al. New nikkomycins by mutasynthesis and directed fermentation[J]. Journal of Antibiotics,1984,37(1):80-82.
[29]Isono K,Nagatsu J,Kawashima Y,et al. Ⅴ.Isolation and characterization of polyoxins C,D,E,F,G,H and I[J]. Agricultural and Biological Chemistry,1967,31:190-199.
[30]李忠福,陈亚敏. 多氧霉素发酵条件的研究[J]. 中小企业管理与科技,2009(10):223.
[31]Barrett A,Lebold S A.(Phenylthio)nitromethane in the total synthesis of polyoxin C[J]. Journal of Organic Chemistry,1990(55):3853-3857.
[32]Mita N,Tamura O,Ishibashi H,et al. Nucleophilic addition reaction of 2-trimethylsilyloxyfuran to N-gulosyl-C-alkoxymethylnitrones:synthetic approach to polyoxin C[J]. Organic Letters,2002,4(7):1111-1114.
[33]Harding E K,Southard J M. A formal synthesis of thymine polyoxin C[J]. Tetrahedron,Asymmetry,2005(16):1845-1854.
[34]Kuzuhara H,Ohrui H,Emoto S. Total synthesis of polyoxin J[J]. Tetrahedron Letters,1973,14(50):5055-5058.
[35]Ghosh A K,Wang Y O. Total synthesis of (+)-polyoxin J[J]. Journal of Organic Chemistry,1999,64(8):2789-2795.
[36]Uchida K,Kato K,Akita H. A convenient synthesis of a N-protected l-carbamoyl-polyoxamic acid derivative:total synthesis of(+)-polyoxin J and (+)-polyoxin L[J]. Synthesis,1999,9:1678-1686.
[37]Uchida K,Kato K,Yamaguchi K,et al. First total syntheses of (+)-polyoxin B and (+)-polyoxin D[J]. Heterocycles,2000,53:2253-2259.
[38]Hori M,Kakiki K,Suzuki S,et al. Studies on the mode of action of polyoxins.Part Ⅲ.Relation of polyoxin structure to chitin synthetase inhibition[J]. Agr Biol Chem,1971,35(8):1280-1291.
[39]Li R,Liu G,Xie Z,et al. PolY,a transcriptional regulator with ATPase activity,directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi[J]. Molecular Microbiology,2010,75(2):349-364.
[40]Luo Y C,Zhang H H,Liu Y Z,et al. An asymmetric approach to 5-O-carbamoyl-2-epi-polyoxamic acid and the total synthesis of 2″-epi-polyoxin J[J]. Tetrahedron,Asymmetry,2009,20(10):1174-1180.
[41]崔琳霞,武艳芍. 3%多抗霉素水剂防治苹果落叶斑点病田间药效试验[J]. 中国农学通报,2008,24(12):394-395.
[42]徐秋菊,韦彦,颜群,等. 0.3%多抗霉素水剂防治水稻稻瘟病田间药效试验研究[J]. 安徽农业科学,2008,36(33):14635,14664.
[43]杨继芝,王继师,龚国淑,等. 多菌灵、多抗霉素及其复配对小麦赤霉病菌的生物活性研究[J]. 安徽农业科学,2010,38(9):4627-4628,4630.
[44]张海宽,周斌. 春雷霉素、多抗霉素防治番茄灰霉病田间药效试验[J]. 农药科学与管理,2010,31(5):48-49.
[45]陶宁,龚道新,杨友才,等. 稻田土壤及水中多抗霉素残留量的分析与检测方法研究[J]. 分析测试学报,2012,31(6):715-719.

相似文献/References:

[1]张爱华,任志成,王壮,等.不同生物源农药对西洋参主要病害的室内抑菌活性及田间防效[J].江苏农业科学,2015,43(11):197.
 Zhang Aihua,et al.Antifungal and field control effects of different fungicides to main pathogens of American ginseng[J].Jiangsu Agricultural Sciences,2015,43(12):197.
[2]龙亚飞,王啸,邱树毅,等.农用多抗霉素对不同地域莱氏野村菌的抑制效果[J].江苏农业科学,2015,43(01):144.
 Long Yafei,et al.Inhibitory effect of agricultural polyoxin on Nomuraea rileyi from different regions[J].Jiangsu Agricultural Sciences,2015,43(12):144.
[3]徐婧,沈晓兰,周捷,等.生物农药茶多酚微乳剂的制备及其对稻瘟病菌的抑制效果[J].江苏农业科学,2017,45(19):191.
 Xu Jing,et al.Preparation of biological pesticide tea polyphenols micro emulsion and its inhibitory effect on Magnaporthe grisea[J].Jiangsu Agricultural Sciences,2017,45(12):191.
[4]刘文,赵蔓菁,张国庆,等.玻璃温室番茄烟粉虱发生动态与防治技术研究[J].江苏农业科学,2018,46(11):87.
 Liu wen,et al.Study on occurrence dynamics and control techniques of Bemisia tabaci in glasshouse[J].Jiangsu Agricultural Sciences,2018,46(12):87.
[5]席新明,邱凌,邱洪臣,等.木醋酸-沼液耦合喷施对苹果树病虫害的防治效果[J].江苏农业科学,2019,47(04):101.
 Xi Xinming,et al.Control effect of wood acetic acid-biogas slurry coupled spraying on diseases and insect pests of apple tree[J].Jiangsu Agricultural Sciences,2019,47(12):101.
[6]王艳,刘琴,黄金金,等.内生放线菌SR-1102对蔬菜立枯病的防效及其促生作用[J].江苏农业科学,2020,48(07):123.
 Wang Yan,et al.Control effect of endophytic actinomycete SR-1102 on rhizoctonia rot and its growth promoting effect[J].Jiangsu Agricultural Sciences,2020,48(12):123.
[7]徐胜,齐振宏,黄炜虹,等.公共农技推广对农户施药行为的影响——基于PSM模型的实证研究[J].江苏农业科学,2021,49(2):229.
 Xu Sheng,et al.Impact of public agricultural technology extension on farmers drug application behavior—Empirical study based on PSM model[J].Jiangsu Agricultural Sciences,2021,49(12):229.
[8]李金龙,玉香甩,罗美云,等.凤庆茶黄蓟马发生规律及农药防控技术[J].江苏农业科学,2021,49(8):118.
 Li Jinlong,et al.Study on occurrence of Scirtothrips dorsalis Hood and control technology of pesticides in Fengqing tea plantation[J].Jiangsu Agricultural Sciences,2021,49(12):118.
[9]徐重新,张江兆,胡晓丹,等.农药联合复配在农作物病虫害防治上的研究进展[J].江苏农业科学,2023,51(4):8.
 Xu Chongxin,et al.Research progress of pesticide combination in crop diseases and insect pests control[J].Jiangsu Agricultural Sciences,2023,51(12):8.
[10]王淼,周杰,陈鸽,等.纳米生物农药的设计及控缓释研究进展[J].江苏农业科学,2023,51(17):9.
 Wang Miao,et al.Research progress on design and controlled release of nano bio-pesticides[JY。]Wang Miao,et al(9)[J].Jiangsu Agricultural Sciences,2023,51(12):9.

备注/Memo

备注/Memo:
收稿日期:2013-04-21
基金项目:江苏省农业科技自主创新资金[编号:CX(12)3060];2011年江苏省创新资金(编号:CXLX12_0452)。
作者简介:胡永红(1968—),女,江苏南通人,博士,教授,主要研究方向为生物农药、生物发酵。Tel:(025)58139928;E-mail:yonghonghu11@126.com。
更新日期/Last Update: 2013-12-25