[1]唐承晨,张纯,王吉永,等.药用植物蛇足石杉内生菌研究进展[J].江苏农业科学,2017,45(07):13-19.
 Tang Chengchen,et al.Research progress of endophyte from Huperzia serrata[J].Jiangsu Agricultural Sciences,2017,45(07):13-19.
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药用植物蛇足石杉内生菌研究进展()

《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第45卷
期数:
2017年07期
页码:
13-19
栏目:
专论与综述
出版日期:
2017-04-20

文章信息/Info

Title:
Research progress of endophyte from Huperzia serrata
作者:
唐承晨12 张纯1 王吉永1 王莉莉1 胡之璧1 黎万奎12
1.上海中医药大学中药研究所/中药新资源与质量标准综合评价国家中医药管理局重点研究室,上海 201203;
2.中国中医科学院/道地药材国家重点实验室培育基地,北京 100700
Author(s):
Tang Chengchenet al
关键词:
蛇足石杉内生菌次级代谢产物生物转化生物活性石杉碱甲
Keywords:
-
分类号:
S182
DOI:
-
文献标志码:
A
摘要:
总结了近年来国内外研究成果,从物种多样性、次级代谢产物、生物活性、生物转化和菌株石杉碱甲高产策略5个方面对蛇足石杉内生菌的研究概况进行综述。蛇足石杉内生菌应用前景广阔,其价值有待于深入研究与开发。本文总结的研究方法亦可为其他植物内生菌的研究提供参考借鉴。
Abstract:
-

参考文献/References:

[1]黎万奎,胡之璧. 内生菌与天然药物[J]. 中国天然药物,2005,3(4):193-199.
[2]邹文欣,谭仁祥. 植物内生菌研究新进展[J]. 植物学报,2001,43(9):881-892.
[3]Strobel G,Daisy B. Bioprospecting for microbial endophytes and their natural products[J]. Microbiology and Molecular Biology Reviews:MMBR,2003,67(4):491-502.
[4]Strobel G,Daisy B,Castillo U,et al. Natural products from endophytic microorganisms[J]. Journal of Natural Products,2004,67(2):257-268.
[5]程丹华,戴克敏. 千层塔的生药学鉴定[J]. 基层中药杂志,1992,6(4):7-9.
[6]朱大元,黄梅芬,王保德,等. 石杉碱戊和石杉碱己的结构[J]. 应用与环境生物学报,1996,2(4):352-355.
[7]蔡龚莉,方帅,张起辉. 蛇足石杉的药学研究进展[J]. 天然产物研究与开发,2015,27(5):931-939.
[8]黎万奎. 蛇足石杉内生真菌生成石杉碱甲的生物技术研究[D]. 上海:上海中医药大学,2006.
[9]龚玉霞. 蛇足石杉内生真菌的分离及生物活性初步研究[D]. 芜湖:安徽师范大学,2007.
[10]吕会芳. 蛇足石杉内生真菌分类鉴定及发酵产物活性的初步研究[D]. 上海:上海中医药大学,2010.
[11]杨迎迎. 药用植物红豆杉和蛇足石杉内生真菌多样性及其生物活性产物的研究[D]. 上海:华东理工大学,2013.
[12]汪涯,曾庆桂,张志斌,等. 蛇足石杉内生真菌分离及其抑制乙酰胆碱酯酶活性研究[J]. 中国中药杂志,2011,36(6):734-740.
[13]徐海杰. 石杉属植物内生菌的多样性及其次生代谢产物的乙酰胆碱酯酶抑制活性研究[D]. 武汉:华中农业大学,2013.
[14]Xiong Z Q,Yang Y Y,Liu Q X,et al. Endophytes in the plant Huperzia serrata:fungal diversity and discovery of a new pentapeptide[J]. Archives of Microbiology,2015,197(3):411-418.
[15]曾庆桂,朱笃,颜日明,等. 一株拮抗真菌的蛇足石杉内生细菌分离鉴定及培养条件优化[J]. 微生物学通报,2008,35(4):512-518.
[16]陈旭玉,甘炳春. 香蕉炭疽病拮抗细菌的分离和初步鉴定[J]. 微生物学杂志,2010,30(5):48-51.
[17]Stierle A,Strobel G,Stierle D. Taxol and taxane production by Taxomyces andreanae,an endophytic fungus of pacific yew[J]. Science,1993,260(5105):214-216.
[18]Zhu D,Wang J,Zeng Q,et al. A novel endophytic huperzine A-producing fungus,Shiraia sp. Slf14,isolated from Huperzia serrata[J]. Journal of Applied Microbiology,2010,109(4):1469-1478.
[19]Zhang Z B,Zeng Q G,Yan R M,et al. Endophytic fungus Cladosporium cladosporioides LF70 from Huperzia serrata produces huperzine A[J]. World Journal of Microbiology & Biotechnology,2011,27(3):479-486.
[20]Shu S H,Zhao X M,Wang W J,et al. Identification of a novel endophytic fungus from Huperzia serrata which produces huperzine A[J]. World Journal of Microbiology & Biotechnology,2014,30(12):3101-3109.
[21]Dong L H,Fan S W,Ling Q Z,et al. Indentification of huperzine A-producing endophytic fungi isolated from Huperzia serrata[J]. World Journal of Microbiology & Biotechnology,2014,30(3):1011-1017.
[22]Su J Q,Yang M H. Huperzine a production by paecilomyces tenuis YS-13,an endophytic fungus isolated from Huperzia serrata[J]. Natural Product Research,2015,29(11):1035-1041.
[23]闵长莉,汪学军. 蛇足石杉产石杉碱甲内生真菌的分离鉴定[J]. 天然产物研究与开发,2013,25(5):590-593.
[24]汪涯,颜日明,曾庆桂,等. 一株产石杉碱甲的蛇足石杉内生真菌的分离和鉴定[J]. 菌物学报,2011,30(2):255-262.
[25]苏经迁,黄彬,邱慧,等. 产生物碱和石杉碱甲蛇足石杉内生真菌的初步研究[J]. 中国药学杂志,2011(19):1477-1481.
[26]董丽辉,范三微,凌庆枝,等. 千层塔中产石杉碱甲内生真菌的研究[J]. 天然产物研究与开发,2014,26(5):650-655.
[27]周树良,杨帆,兰时乐,等. 千层塔内生真菌SHB发酵产石杉碱甲条件的研究[J]. 微生物学杂志,2009,29(3):32-36.
[28]韩文霞,宋涛,杨时珍,等. 野生蛇足石杉产生物碱和石杉碱甲内生真菌分离鉴定[J]. 国际药学研究杂志,2015(4):507-512.
[29]谢丹凤. 福建蛇足石杉内生真菌的分离鉴定与石杉碱甲的HPLC检测[D]. 福州:福建农林大学,2009.
[30]黎万奎,周吉燕,林子为,等. 超声波提取蛇足石杉内生真菌2F09P03B中石杉碱甲的研究[J]. 中国药学杂志,2008,43(8):578-581.
[31]杨晓军,郭海清,高霞,等. 内生真菌YD-01次生代谢产物的研究Ⅰ[J]. 中国药科大学学报,2006,37(5):479-480.
[32]戈惠明,谭仁祥. 共生菌——新活性天然产物的重要来源[J]. 化学进展,2009,21(1):30-46.
[33]Aly A H,Debbab A,Kjer J,et al. Fungal endophytes from higher plants:a prolific source of phytochemicals and other bioactive natural products[J]. Fungal Diversity,2010,41(1):1-16.
[34]Shan W G,Ying Y M,Yu H,et al. Diketopiperazine alkaloids from Penicillium spp.HS-3,an endophytic fungus in Huperzia serrata[J]. Helvetica Chimica Acta,2010,93(4):772-776.
[35]Ying Y M,Shan W G,Liu Wen-hong,et al. Alkaloids and nucleoside derivatives from a fungal endophyte of Huperzia serrata[J]. Chemistry of Natural Compounds,2013,49(1):184-186.
[36]Zhan Z,Jin J,Ying Y,et al. Furanone derivatives from Aspergillus sp. XW-12,an endophytic fungus in Huperzia serrata[J]. Helvetica Chimica Acta,2011,94(8):1454-1458.
[37]Ying Y M,Zhan Z J,Ding Z S,et al. Bioactive metabolites from Penicillium sp. P-1,a fungal endophyte in Huperzia serrata[J]. Chemistry of Natural Compounds,2011,47(4):541-544.
[38]Xiang J,Shan W-g,Liang D,et al. N-Bearing furanone derivatives from an endophytic fungus in Huperzia serrata[J]. Helvetica Chimica Acta,2013,96(5):997-1003.
[39]Ying Y M,Zheng Z Z,Zhang L W,et al. Rare C-25 steroids produced by Penicillium chrysogenum P1X,a fungal endophyte of Huperzia serrata[J]. Helvetica Chimica Acta,2014,97(1):95-101.
[40]Ma T T,Shan W G,Ying Y M,et al. Xanthones with alpha-Glucosidase inhibitory activities from Aspergillus versicolor,a fungal endophyte of Huperzia serrata[J]. Helvetica Chimica Acta,2015,98(1):148-152.
[41]Chen Y M,Yang Y H,Li X N,et al. Diterpenoids from the endophytic fungus Botryosphaeria sp. P483 of the Chinese herbal medicine Huperzia serrata[J]. Molecules,2015,20(9):16924-16932.
[42]Ying Y M,Tong C P,Wang J W,et al. Ceriponol P,the first example of monocyclic tremulane sesquiterpene produced by Ceriporia lacerate a fungal endophyte of Huperzia serrata[J]. Journal of Chemical Research,2014,38(5):304-305.
[43]Ying Y M,Shan W G,Zhang L W,et al. Ceriponols A-K,tremulane sesquitepenes from Ceriporia lacerate HS-ZJUT-C13A,a fungal endophyte of Huperzia serrata[J]. Phytochemistry,2013,95(6):360-367.
[44]Ying Y M,Shan W G,Zhang L,et al. Lanostane triterpenes from Ceriporia lacerate HS‐ZJUT‐C13A,a fungal endophyte of Huperzia serrata[J]. Helvetica Chimica Acta,2013,96(11):2092-2097.
[45]Shan W G,Liang D E,Ying Y M,et al. Two new tremulane sesquiterpenoids from Ceriporia lacerate,an endophytic fungus of Huperzia serrata[J]. Journal of Chemical Research,2012(6):365-366.
[46]付少彬,闫松,张芸,等. 7株蛇足石杉内生真菌拮抗4种致病菌的研究[J]. 生物技术世界,2015,87(2):62-62.
[47]董丽辉,范三微,凌庆枝,等. 蛇足石杉内生真菌清除DPPH·与抑制乙酰胆碱酯酶活性研究[J]. 湖北农业科学,2014,53(4):888-893.
[48]颜日明,李希茜,汪涯,等. 蛇足石杉内生真菌Shiraia sp.Slf14化学成分及其抑菌活性研究[J]. 天然产物研究与开发,2014,26(9):1393-1397.
[49]Wang Y,Zeng Q G,Zhang Z B,et al. Antagonistic bioactivity of an endophytic bacterium H-6[J]. African Journal of Biotechnology,2010,9(37):6140-6145.
[50]龚玉霞,蒋继宏,陈凤美,等. 蛇足石杉内生真菌的分离和抗植物病原真菌活性[J]. 安徽师范大学学报(自然科学版),2007,30(6):689-692.
[51]李娜,宁正祥,陈钧. 蛇足石杉内生真菌生物学性状及发酵产物研究[J]. 江苏农业科学,2009(1):184-186.
[52]李娜,陈钧,承曦,等. 真菌对蛇足石杉扦插生根的影响及其机理研究[J]. 江苏农业科学,2007(5):181-184.
[53]李晓誉,陈峰阳,徐世芳,等. 千层塔内生真菌G324-4次生代谢产物化学成分及乙酰胆碱酯酶抑制活性研究[J]. 中华中医药学刊,2013,31(1):89-90.
[54]刘海元,王明兹,吴水生,等. 乙酰胆碱酯酶活性筛选模型对蛇足石杉内生真菌的筛选研究[J]. 海峡药学,2012,24(3):238-241.
[55]王莉莉,吕会芳,张丽,等. 蛇足石杉内生真菌抗乙酰胆碱酯酶活性筛选及分类鉴定[J]. 中国中药杂志,2012,37(24):3701-3705.
[56]汪涯,曾庆桂,张志斌,等. 蛇足石杉内生真菌分离及其抑制乙酰胆碱酯酶活性研究[J]. 中国中药杂志,2011,36(6):734-740.
[57]承曦,陈钧,朱大元. 蛇足石杉内生真菌g5的乙酰胆碱酯酶抑制活性初步研究[J]. 微生物学通报,2008,35(11):1764-1768.
[58]马骁驰,果德安. 中药活性成分生物转化的研究思路与方法[J]. 中国天然药物,2007,5(3):162-168.
[59]Ying Y M,Shan W G,Zhan Z J. Biotransformation of huperzine A by a fungal endophyte of Huperzia serrata furnished sesquiterpenoid-alkaloid hybrids[J]. Journal of Natural Products,2014,77(9):2054-2059.
[60]Fu S B,Yang J S,Cui J L,et al. Biotransformation of ursolic acid by an endophytic fungus from medicinal plant Huperzia serrata[J]. Chemical & Pharmaceutical Bulletin,2011,59(9):1180-1182.
[61]Fu S B,Yang J S,Cui J L,et al. Multihydroxylation of ursolic acid by Pestalotiopsis microspora isolated from the medicinal plant Huperzia serrata[J]. Fitoterapia,2011,82(7):1057-1061.
[62]马义雯. 刺囊酸的微生物转化[D]. 合肥:安徽中医药大学,2013.
[63]黎万奎,周吉燕,林子为,等. 蛇足石杉内生真菌2F09P03B产石杉碱甲发酵条件的研究[J]. 中国医药生物技术,2007,2(4):254-259.
[64]王吉祥. 一株产石杉碱甲蛇足石杉内生真菌的分离及其发酵条件的初步研究[D]. 南昌:江西师范大学,2010.
[65]Zhao X M,Wang Z Q,Shu S H,et al. Ethanol and methanol can improve huperzine A production from endophytic Colletotrichum gloeosporioides ES026[J]. PLoS One,2013,8(4):e61777.
[66]Yan R M,Zhang Z B,Wang Y,et al. Efficient strategy for maintaining and enhancing the huperzine A production of Shiraia sp. Slf14 through inducer elicitation[J]. Journal of Industrial Microbiology & Biotechnology,2014,41(7):1175-1179.
[67]周树良,温拥军,徐宁,等. 物理与化学诱变筛选产石杉碱甲高产菌株的研究[J]. 湖南农业科学,2009(10):1-3,8.
[68]张晓琼,郑雅媗,张方方,等. 原生质体诱变选育石杉碱甲高产菌株[J]. 海峡药学,2015,27(11):238-242.
[69]Zhang G W,Wang W J,Zhang X M,et al. De novo RNA sequencing and transcriptome analysis of Colletotrichum gloeosporioides ES026 reveal genes related to biosynthesis of huperzine A[J]. PLoS One,2015,10(3):e0120809.
[70]王文娟. 胶胞炭疽菌ESO26 T-DNA插入突变体库的构建[D]. 武汉:华中农业大学,2014.

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备注/Memo

备注/Memo:
收稿日期:2016-02-22
基金项目:国家自然科学基金重点项目(编号:81130070);国家科技支撑计划(编号:2012BAI29B02)。
作者简介:唐承晨,硕士研究生,研究方向为中药生物技术与资源开发利用。Tel:(021)51322574;E-mail:tangchengchen@foxmail.com。
通信作者:黎万奎,副研究员,硕士生导师,研究方向为中药生物技术与资源开发利用。E-mail:bio5210@126.com。
更新日期/Last Update: 2017-04-05