|本期目录/Table of Contents|

[1]李莉,任红艳,毕延震,等.基因编辑技术的新进展及展望[J].江苏农业科学,2018,46(23):5-10.
　Li Li,et al.New progress and prospect of gene editing technology[J].Jiangsu Agricultural Sciences,2018,46(23):5-10.
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基因编辑技术的新进展及展望(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第46卷
期数:
2018年第23期
页码:
5-10
栏目:
专论与综述
出版日期:
2018-12-05

文章信息/Info

Title:
New progress and prospect of gene editing technology
作者:
李莉;  任红艳;  毕延震;  华文君;  华再东;  张立苹;  郑新民
湖北省农业科学院畜牧兽医研究所/动物胚胎工程及分子育种湖北省重点实验室，湖北武汉 430064
Author(s):
Li Li; et al
关键词:
基因编辑技术; CRISPR/Cas; NgAgo; SGN; ADAR; PNA; TD
Keywords:
-
分类号:
Q78
DOI:
-
文献标志码:
A
摘要:
随着生物技术的不断发展，传统的转基因技术由于其不能定点整合、遗传不稳定等难以解决基因定点改良与改造问题，所以科研工作者一直致力于寻找简单、高效率、低成本、精准定位等优势的新型转基因技术，掀起了一股基因编辑技术研究的热潮，新的基因编辑技术不断涌现。本文从成簇有规律间隔的短回文重复序列及相关蛋白(CRISPR/Cas)的技术改进与新应用以及一些新出现的技术，如NgAgo技术、结构引导的核酸内切酶(SGN)、腺苷脱氨酶(ADAR)、肽核酸(PNA)、5′末端突出的复合物DNA(TD)等方面，阐述基因编辑技术的新进展，并展望基因技术的应用前景，希望能够为相关研究者提供参考
Abstract:
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备注/Memo

备注/Memo:
收稿日期：2017-07-26
基金项目：国家自然科学基金(编号：31772577)；转基因生物新品种培育重大专项(编号：2016ZX08010003-006)；湖北省农业科技创新计划(编号：2018-620-004-001)；湖北省农业科学院竞争性项目(编号：2016jzxjh013)；东南大学生物电子学国家重点实验室开放研究基金。
作者简介：李莉(1972—)，女，湖北红安人，副研究员，主要从事动物生物技术研究。E-mail：136286125@qq.com。
通信作者：郑新民，研究员，主要从事动物生物技术研究。E-mail：anbit20@163.com。
更新日期/Last Update: 2018-12-05