|本期目录/Table of Contents|

[1]刘莉云,高璐,薛永来,等.甲状腺激素干扰物对鱼类甲状腺轴的干扰效应研究进展[J].江苏农业科学,2018,46(14):8-14.
 Liu Liyun,et al.Research progress on interference effects of thyroid hormone disrupting chemicals on hypothalamus-pituitary-thyroid axis of fish[J].Jiangsu Agricultural Sciences,2018,46(14):8-14.
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甲状腺激素干扰物对鱼类甲状腺轴
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第46卷
期数:
2018年第14期
页码:
8-14
栏目:
专论与综述
出版日期:
2018-07-25

文章信息/Info

Title:
Research progress on interference effects of thyroid hormone disrupting chemicals on hypothalamus-pituitary-thyroid axis of fish
作者:
刘莉云 高璐 薛永来 杜道林
江苏大学环境与安全工程学院,江苏镇江 212013
Author(s):
Liu Liyunet al
关键词:
鱼类甲状腺激素干扰物下丘脑-垂体-甲状腺轴干扰效应作用机制研究进展
Keywords:
-
分类号:
X174
DOI:
-
文献标志码:
A
摘要:
甲状腺激素干扰物(thyroid-disrupting chemicals,简称TDCs)能够通过干扰鱼体甲状腺激素(thyroid hormones,简称THs)的合成、转运、转化及代谢等过程造成其水平紊乱,影响甲状腺组织的结构和生理功能。为更系统地阐述TDCs对鱼类甲状腺轴的干扰,综述各类TDCs对鱼类下丘脑-垂体-甲状腺轴(hypothalamus-pituitary-thyroid axis,简称HPT)干扰的最新研究进展,归纳分析TDCs对鱼类甲状腺激素水平、甲状腺组织病理学变化、HPT轴相关基因表达以及生长发育指标的干扰作用,在基因水平上探讨其可能的作用机制,并就水体中TDCs对鱼类HPT轴干扰效应的未来研究方向进行展望。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2017-02-05
基金项目:国家自然科学基金(编号:31100379、31601380);江苏省自然科学基金(编号:BK20130499、BK2012274)。
作者简介:刘莉云(1991—),女,山东临沂人,硕士研究生,从事环境毒理学研究。E-mail:981219794@qq.com。
通信作者:薛永来,博士,副教授,从事环境毒理学研究。E-mail:xueyonglai@sina.com。
更新日期/Last Update: 2018-07-20