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[1]蔡刚志,华再东,毕延震,等.SCD基因与猪脂肪酸代谢(综述)[J].江苏农业科学,2019,47(20):24-28.
　Cai Gangzhi,et al.SCD gene and fatty acid metabolism in pigs：a review[J].Jiangsu Agricultural Sciences,2019,47(20):24-28.
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SCD基因与猪脂肪酸代谢(综述)(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第47卷
期数:
2019年第20期
页码:
24-28
栏目:
专论与综述
出版日期:
2019-11-18

文章信息/Info

Title:
SCD gene and fatty acid metabolism in pigs：a review
作者:
蔡刚志1; 2;  华再东2;  毕延震2;  陈彬1
1.高原山地动物遗传育种与繁殖省部共建教育部重点实验室/贵州省动物遗传育种与繁殖重点实验室/贵州大学动物科学学院，
贵州贵阳 550025；2.湖北省农业科学院畜牧兽医研究所/动物胚胎工程及分子育种湖北省重点实验室，湖北武汉 430064
Author(s):
Cai Gangzhi; et al
关键词:
SCD基因; 限速酶; 猪肉; 脂肪酸; 代谢; 基因功能; 调控机制
Keywords:
-
分类号:
Q54；Q786
DOI:
-
文献标志码:
A
摘要:
硬脂酰辅酶A去饱和酶(stearoyl-CoA desaturase，SCD)是催化饱和脂肪酸(SFAs)形成单不饱和脂肪酸(MUFAs)的限速酶，在猪等大多数动物中已鉴定出2种SCD亚型(SCD1和SCD5)。这2个亚型的组织表达和作用方式存在差异，其中SCD1主要在脂肪组织中表达，其活性受单核苷酸多态性(SNP)、miRNA、DNA甲基化等因素调控；SCD5主要在脑组织中表达，与神经细胞的增殖和分化密切相关，但SCD5在脑外组织的功能尚未阐明，具有广泛的研究前景。因此，深入研究SCD的基因功能和调控机制对改善猪肉的脂肪酸组成、提高猪肉品质具有重要意义。
Abstract:
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备注/Memo

备注/Memo:
收稿日期：2018-07-13
基金项目：国家自然科学基金(编号：31772577)；湖北省自然科学基金“杰出青年”项目(编号：2018CFA043)；湖北省农业科技创新中心项目(编号：2018-620-004-001)；湖北省农业科学院领军人才培养计划。
作者简介：蔡刚志(1993—)，男，贵州毕节人，硕士研究生，从事动物遗传育种与种质资源创新研究。E-mail：1298275743@qq.com。
通信作者：毕延震，博士，研究员，主要从事为分子遗传学研究，E-mail：sukerbyz@126.com；陈彬，博士，副教授，主要从事为分子遗传学研究，E-mail：chenbin6262@aliyun.com。
更新日期/Last Update: 2019-10-20