|本期目录/Table of Contents|

[1]王黎曌,薛永来,高璐,等.纳米氧化铜对斑马鱼甲状腺系统的干扰效应[J].江苏农业科学,2019,47(14):202-205.
　Wang Lizhao,et al.Interference effects of CuO NPs on thyroid system in zebrafish[J].Jiangsu Agricultural Sciences,2019,47(14):202-205.
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纳米氧化铜对斑马鱼甲状腺系统的干扰效应(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第47卷
期数:
2019年第14期
页码:
202-205
栏目:
畜牧兽医与水产蚕桑
出版日期:
2019-08-10

文章信息/Info

Title:
Interference effects of CuO NPs on thyroid system in zebrafish
作者:
王黎曌;  薛永来;  高璐;  杜道林
江苏大学环境与安全工程学院，江苏镇江 212013
Author(s):
Wang Lizhao; et al
关键词:
纳米氧化铜; 斑马鱼; 甲状腺滤泡; 激素; 基因
Keywords:
-
分类号:
S941.91；X174
DOI:
-
文献标志码:
A
摘要:
目前纳米技术发展和应用以指数形式快速增长，纳米氧化铜(copper oxide nanoparticles，CuO NPs)因在吸光性、磁性、化学催化和热传导等方面具有独特的优势而得到广泛应用，近期关于CuO NPs对细胞、动物胚胎和植物的毒性报道日益增多，但是关于CuO NPs对鱼类甲状腺系统的报道相对较少。因此，本试验选用斑马鱼作为研究对象，从细胞形态、激素水平和基因层面研究了纳米氧化铜对斑马鱼甲状腺系统造成的干扰效应。结果表明，CuO NPs可损伤甲状腺滤泡结构，改变上皮细胞形态，诱导甲状腺激素T3和T4上升并且造成代谢酶编码基因ugt1ab的表达下调。
Abstract:
-

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备注/Memo

备注/Memo:
收稿日期：2018-05-02
基金项目：国家自然科学基金(编号：31100379、31601380)；江苏大学高级人才基金(编号：10JGD056)。
作者简介：王黎曌(1991—)，女，江苏盐城人，硕士研究生，主要研究方向为环境毒理学。E-mail：wanglizhao1111@163.com。
通信作者：薛永来，博士，副教授，主要研究方向为环境毒理学、环境生物学。E-mail：xueyonglai@sina.com。
更新日期/Last Update: 2019-07-20