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[1]倪敏舒,陈丽,鲍熹,等.内质网应激与病毒感染(综述)[J].江苏农业科学,2022,50(17):180-186.
　Ni Minshu,et al.Endoplasmic reticulum stress and virus infection： a review[J].Jiangsu Agricultural Sciences,2022,50(17):180-186.
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内质网应激与病毒感染(综述)(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第50卷
期数:
2022年第17期
页码:
180-186
栏目:
畜牧兽医与水产蚕桑
出版日期:
2022-09-05

文章信息/Info

Title:
Endoplasmic reticulum stress and virus infection： a review
作者:
倪敏舒1; 2; 陈丽2; 鲍熹2; 恽君雯2; 3; 徐悦2; 冯磊1; 2
1.江苏大学药学院，江苏镇江 212013； 2.江苏省农业科学院动物免疫工程研究所，江苏南京 210014； 3.扬州大学，江苏扬州 225009
Author(s):
Ni Minshu; et al
关键词:
内质网应激; 病毒感染; 未折叠蛋白反应; 代谢综合征
Keywords:
-
分类号:
R511；S852.65
DOI:
-
文献标志码:
A
摘要:
内质网在细胞内负责蛋白质和脂类合成、加工及成熟。当病毒感染细胞时，也同样会利用内质网完成病毒本身蛋白质合成。同时，大量病毒蛋白堆积，会诱发内质网的应激反应，随后内质网调控各种信号通路维持细胞稳态与生命体的整体利益，进而引起细胞自噬及凋亡、代谢综合征。有些病毒会通过改变对自身复制不利应激通路的蛋白表达，同时，维持对自身有益的方面来加强病毒本身的复制。本文对内质网应激和未折叠蛋白反应信号通路及对一些病毒感染与内质网应激的相互作用和一些病毒感染导致的代谢综合征进行简要综述，总结了关于内质网应激与病毒感染的最新研究成果，旨在为内质网应激有关的抗病毒感染研究提供思路。
Abstract:
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备注/Memo

备注/Memo:
收稿日期：2021-09-23
基金项目：江苏省重点研发计划(编号：BE2020407)。
作者简介：倪敏舒(1996—)，男，江苏常州人，硕士研究生，主要从事内质网应激和病毒感染研究。E-mail：847497386@qq.com。
通信作者：冯磊，副研究员，主要从事兽用生物制品研究。E-mail：fenglei@jaas.ac.cn。
更新日期/Last Update: 2022-09-05