|本期目录/Table of Contents|

[1]李永峰,王克华,窦套存,等.蛋鸡资源群体的小肠质量全基因组关联分析[J].江苏农业科学,2022,50(22):165-170.
　Li Yongfeng,et al.Genome-wide association analysis for small intestine weight of laying hens[J].Jiangsu Agricultural Sciences,2022,50(22):165-170.
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蛋鸡资源群体的小肠质量全基因组关联分析(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第50卷
期数:
2022年第22期
页码:
165-170
栏目:
畜牧兽医与水产蚕桑
出版日期:
2022-11-20

文章信息/Info

Title:
Genome-wide association analysis for small intestine weight of laying hens
作者:
李永峰; 王克华; 窦套存; 胡玉萍; 郭军; 王星果; 马猛; 曲亮
江苏省家禽科学研究所，江苏扬州 225125
Author(s):
Li Yongfeng; et al
关键词:
蛋鸡; 小肠质量; GWAS; 遗传结构
Keywords:
-
分类号:
S831.2
DOI:
-
文献标志码:
A
摘要:
小肠是鸡重要的营养消化吸收器官，在蛋鸡生长和生产发挥重要作用，小肠质量是反映肠道发育情况的重要生理指标，有必要对其遗传结构进行研究。利用白来航鸡与东乡绿壳蛋鸡杂交构建F2代资源群体，采用600K鸡SNP芯片对F2代1 512羽个体进行基因型检测，通过PLINK软件对小肠质量性状进行全基因组关联分析(GWAS)。结果显示，十二指肠、空肠和回肠的遗传力分别为0.32、0.28、0.26，说明小肠质量表现出中等遗传力水平。GWAS共鉴定出185、201、36个SNP分别与十二指肠、空肠、回肠质量显著相关(共422个SNP)，其中，421个SPN位于1号染色体166.6~173.2 Mb区域，说明该区域与小肠质量关系密切。共有28个SNP与3段小肠质量均显著相关，其中，6个SNP位于对应4个候选基因(FOXO1、CKAP2、CAB39L和MRPS31)的内含子区，它们可能与小肠质量密切相关。通过GWAS分析，初步筛选出与蛋鸡小肠质量性状相关的6个SNP和4个候选基因，可为性状的遗传机制解析和分子育种提供理论依据。
Abstract:
-

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备注/Memo

备注/Memo:
收稿日期：2021-11-15
基金项目：江苏省种业振业揭榜挂帅项目(编号：JBGS［2021］104)；江苏省农业重大新品种创制(编号：PZCZ201729)；现代农业产业技术体系建设专项(编号：CARS-40-K01)。
作者简介：李永峰(1989—)，男，河南新乡人，硕士，助理研究员，主要从事家禽遗传育种与繁殖研究。E-mail：liyf0120@163.com。
通信作者：曲亮，博士，副研究员，主要从事家禽遗传育种与繁殖研究。E-mail：676542516@qq.com。
更新日期/Last Update: 2022-11-20