|本期目录/Table of Contents|

[1]李向阳,汤宏,张国辉.比较基因组分析斯氏假单胞菌遗传多样性及固氮基因岛进化机制[J].江苏农业科学,2017,45(01):33-38.
　Li Xiangyang,et al.Comparative genome analysis of genetic diversity and evolution of nitrogen-fixation island in Pseudomonas stutzeri[J].Jiangsu Agricultural Sciences,2017,45(01):33-38.
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比较基因组分析斯氏假单胞菌遗传多样性
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第45卷
期数:
2017年01期
页码:
33-38
栏目:
生物技术
出版日期:
2017-01-05

文章信息/Info

Title:
Comparative genome analysis of genetic diversity and evolution of nitrogen-fixation island in Pseudomonas stutzeri
作者:
李向阳1; 2;  汤宏1;  张国辉1
1.凯里学院环境与生命科学学院，贵州凯里 556011；2.复旦大学环境科学与工程系，上海杨浦 200433
Author(s):
Li Xiangyang; et al
关键词:
斯氏假单胞菌; 固氮基因岛; 比较基因组; 基因组变异型; 多样性
Keywords:
-
分类号:
S182
DOI:
-
文献标志码:
A
摘要:
对5株固氮与11株非固氮斯氏假单胞菌(Pseudomonas stutzeri)基因组开展综合比较分析，从基因组水平上研究斯氏假单胞菌种内遗传多样性及其固氮基因岛进化机制。核心与元基因组分析发现，16个斯氏假单胞菌拥有的独特基因数占元基因数的46.37%；基于平均核苷酸相似度分析，这16个菌株被划分为11种不同的基因组变异型，表明斯氏假单胞菌基因组异质化程度高。固氮基因岛及进化树分析表明，5株固氮菌属于3种不同基因组变异型，它们的固氮基因岛及其侧翼序列保守性好，而且固氮酶基因进化树与菌株谱系进化树呈现高度一致性。据此推测，斯氏假单胞菌祖先可能通过水平基因转移的方式获得固氮基因岛，从而转变为固氮菌，但是在后期进化过程中，绝大部分固氮菌株丢失了固氮基因岛。
Abstract:
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备注/Memo

备注/Memo:
收稿日期：2015-12-27
基金项目：国家自然科学基金(编号：21507012)；中国博士后科学基金(编号：黔教合KY字［2015］395)；贵州省教育厅自然科学研究项目［重点项目］［(编号：KY2015395)；凯里学院博士专项基金(编号：BS201412)。
作者简介：李向阳(1984—)，男，湖北监利人，博士，副教授，主要从事环境微生物学及比较基因组学研究。E-mail：lixiangyang1984@gmail.com。
更新日期/Last Update: 2017-01-05