|本期目录/Table of Contents|

[1]冯颖,张晓璐,鲍晚秋,等.基于全基因组测序的耐盐金黄色葡萄球菌ZS01的耐盐机制研究[J].江苏农业科学,2022,50(24):50-58.
 Feng Ying,et al.Study on salt tolerance mechanism of Staphylococcus aureus ZS01 based on whole genome sequencing[J].Jiangsu Agricultural Sciences,2022,50(24):50-58.
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基于全基因组测序的耐盐金黄色葡萄球菌ZS01的耐盐机制研究(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第50卷
期数:
2022年第24期
页码:
50-58
栏目:
生物技术
出版日期:
2022-12-20

文章信息/Info

Title:
Study on salt tolerance mechanism of Staphylococcus aureus ZS01 based on whole genome sequencing
作者:
冯颖1234张晓璐1鲍晚秋1张霞1王心雨1刘伟12明庭红34苏秀榕34
1.通化师范学院生命科学学院,吉林通化 134002; 2.通化师范学院吉林省长白山生物种质资源评价及应用重点实验室,吉林通化 134002;3.宁波大学农产品质量安全危害因子与风险防控国家重点实验室,浙江宁波 315211; 4.宁波大学海洋学院,浙江宁波 315832
Author(s):
Feng Yinget al
关键词:
耐盐金黄色葡萄球菌全基因组测序耐盐分子机制GO分类KEGG途径
Keywords:
-
分类号:
S182
DOI:
-
文献标志码:
A
摘要:
为探讨金黄色葡萄球菌(Staphylococcus aureus)耐受盐胁迫的分子机制,以从盐渍水产品中分离的高耐盐菌株S. aureus ZS01和标准菌株S. aureus ATCC 27217作为研究对象,利用二代全基因组测序平台,采用比较组学方法,结合胁迫后金黄色葡萄球菌生长活性和细胞壁通透性的变化,从DNA层面阐明金黄色葡萄球菌耐受盐胁迫的分子机制。结果表明,S. aureus ZS01特异的基因GO分类统计主要涉及膜的整体组件、胞外区、DNA结合和发病机制;KEGG途径主要集中在细胞群落原核生物、传染病:细菌、膜转运、复制和修复,其中与耐盐相关的基因主要涉及双组分信号转导系统、ABC转运系统、转录调控因子和DNA损伤修复,这些基因很可能就是S. aureus ZS01较标准菌株更耐盐的主要原因。
Abstract:
-

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备注/Memo

备注/Memo:
收稿日期:2022-02-23
基金项目:国家重点研发计划(编号:2019YFD0900101);吉林省教育厅科学研究项目(编号:JJKH20210531KJ);通化师范学院非师范专业学生创新训练项目(编号:CS2020083)。
作者简介:冯颖(1983—),女,吉林通化人,博士,副教授,主要从事水生生物技术研究。E-mail: 32627580@qq.com。
通信作者:苏秀榕,博士,教授,主要从事食品科学与工程研究。E-mail: suxiurong_public@163.com。
更新日期/Last Update: 2022-12-20