|本期目录/Table of Contents|

[1]吴慧珍,王洋,谢正露.哺乳动物精子运动的调节综述[J].江苏农业科学,2020,48(09):60-66.
 Wu Huizhen,et al.Regulation of mammalian sperm motility: a review[J].Jiangsu Agricultural Sciences,2020,48(09):60-66.
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哺乳动物精子运动的调节综述(PDF)
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第48卷
期数:
2020年第09期
页码:
60-66
栏目:
专论与综述
出版日期:
2020-05-05

文章信息/Info

Title:
Regulation of mammalian sperm motility: a review
作者:
吴慧珍 王洋 谢正露
福建农林大学动物科学学院/福建农林大学金山学院,福建福州 350002
Author(s):
Wu Huizhenet al
关键词:
哺乳动物精子鞭毛雄性不育分子遗传学
Keywords:
-
分类号:
Q492
DOI:
-
文献标志码:
A
摘要:
哺乳动物受精需要精子运动到雌性生殖道与卵子发生融合,精子的激活运动和超激活运动为精子到达受精部位完成受精过程提供保障。活力低下的精子或无活力的精子占比很高时将对雄性生育能力产生不利影响,因此对精子活力进行分析是评估雄性生育能力的核心部分。精子的运动性对生育能力至关重要,但目前弱精子症仍然只是一个病理性的描述,对其潜在原因还了解不多,哺乳动物精子运动的研究具有重要的应用价值。本文对精子超显微结构及精子运动的几种调控机制进行阐述,旨在对临床研究精子运动的生理过程有更全面的理解,为弱精子症的治疗提供理论基础。
Abstract:
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参考文献/References:

[1]Suarez S S,Osman R A. Initiation of hyperactivated flagellar bending in mouse sperm within the female reproductive tract[J]. Biology of Reproduction,1987,36(5):1191-1198.
[2]Katz D F,Vanagimachi R. Movement characteristics of hamster spermatozoa within the oviduct[J]. Biology of Reproduction,1980,22(4):759-764.
[3]Gaddum-Rosse P. Some observations on sperm transport through the uterotubal junction of the rat[J]. The American Journal of Anatomy,1981,160(3):333-341.
[4]Yanagimachi R. The movement of golden hamster spermatozoa before and after capacitation[J]. Journal of Reproduction and Fertility,1970,23(1):193-196.
[5]Ishijima S. Dynamics of flagellar force generated by a hyperactivated spermatozoon[J]. Reproduction,2011,142(3):409-415.
[6]Fraser L R,Quinn P J. A glycolytic product is obligatory for initiation of the sperm acrosome reaction and whiplash motility required for fertilization in the mouse[J]. Journal of Reproduction and Fertility,1981,61(1):25-35.
[7]Boatman D E,Robbins R S. Bicarbonate:carbon-dioxide regulation of sperm capacitation,hyperactivated motility,and acrosome reactions[J]. Biology of Reproduction,1991,44(5):806-813.
[8]Ounjai P,Kim K D,Lishko P V,et al. Three-dimensional structure of the bovine sperm connecting piece revealed by electron cryotomography[J]. Biology of Reproduction,2012(73):1-9.
[9]Fiedler S E,Dudiki T,Vijayaraghavan S,et al. Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility,phosphorylation,and fibrous sheath integrity[J]. Biology of Reproduction,2013,88(41):1-10.
[10]Turner R M. Moving to the beat:a review of mammalian sperm motility regulation[J]. Reproduction Fertility and Development,2006,18(1/2):25-38.
[11]Barratt C L,Publicover S J. Sperm are promiscuous and catsper is to blame[J]. EMBO Journal,2012,31(7):1624-1626.
[12]Du Plessis S S,Agarwal A,Mohanty G,et al. Oxidative phosphorylation versus glycolysis:what fuel do spermatozoa use?[J]. Asian Journal of Andrology,2015,17(2):230-235.
[13]Lin J,Okada K,Raytchev M,et al. Structural mechanism of the dynein power stroke[J]. Nature Cell Biology,2014(5):479-485.
[14]Ishijima S. Self-sustained oscillatory sliding movement of doublet microtubules and flagellar bend formation.[J]. PLoS One,2016(2):e148880.
[15]Luck D,Piperno G,Ramanis Z,et al. Flagellar mutants of chlamydomonas:studies of radial spoke-defective strains by dikaryon and revertant analysis[J]. Proceedings of the National Academy of Sciences of the United States of America,1977,74(8):3456-3460.
[16]Linck R W,Chemes H,Albertini D F. The axoneme:the propulsive engine of spermatozoa and cilia and associated ciliopathies leading to infertility[J]. Journal of Assisted Reproduction and Genetics,2016,33(2):141-156.
[17]Weil D,Blanchard S,Kaplan J,et al. Defective myosin VIIA gene responsible for usher syndrome type 1B[J]. Nature,1995,374(6517):60-61.
[18]Hunter D G,Fishman G A,Kretzer F L. Abnormal axonemes in X-linked retinitis pigmentosa[J]. Archives of Ophthalmology,1988,106(3):362-368.
[19]Gastmann O,Burfeind P,Gunther E,et al. Sequence,expression,and chromosomal assignment of a human sperm outer dense fiber gene[J]. Molecular Reproduction and Development,1993,36(4):407-418.
[20]Morales C R,Oko R,Clermont Y. Molecular cloning and developmental expression of an mRNA encoding the 27 kDa outer dense fiber protein of rat spermatozoa[J]. Molecular Reproduction and Development,1994,37(2):229-240.
[21]Zarsky H A,Tarnasky H A,Cheng M,et al. Novel RING finger protein OIP1 binds to conserved amino acid repeats in sperm tail protein ODF1[J]. Biology of Reproduction,2003,68(2):543-552.
[22]Du J,Tao J,Kleinhans F W,et al. Water volume and osmotic behaviour of mouse spermatozoa determined by electron paramagnetic resonance[J]. Journal of Reproduction and Fertility,1994,101(1):37-42.
[23]Lindemann C B,Lesich K A. Functional anatomy of the mammalian sperm flagellum[J]. Cytoskeleton,2016,73(11):652-669.
[24]Lindemann C B,Lesich K A. Functional anatomy of the mammalian sperm flagellum[J]. Cytoskeleton,2016,73(11):652-669.
[25]Lindemann C B,Orlando A,Kanous K S. The flagellar beat of rat sperm is organized by the interaction of two functionally distinct populations of dynein bridges with a stable central axonemal partition[J]. Journal of Cell Science,1992,102(Pt 2):249-260.
[26]Si Y,Okuno M. Extrusion of microtubule doublet outer dense fibers 5-6 associating with fibrous sheath sliding in mouse sperm flagella[J]. The Journal of Experimental Zoology,1995,273(4):355-362.
[27]Fulcher K D,Welch J E,Klapper D G,et al. Identification of a unique mu-class glutathione S-transferase in mouse spermatogenic cells[J]. Molecular Reproduction and Development,1995,42(4):415-424.
[28]Bunch D O,Welch J E,Magyar P L,et al. Glyceraldehyde 3-phosphate dehydrogenase-S protein distribution during mouse spermatogenesis[J]. Biology of Reproduction,1998,58(3):834-841.
[29]Storey B T,Kayne F J. Energy metabolism of spermatozoa.V.The Embden-Myerhof pathway of glycolysis:activities of pathway enzymes in hypotonically treated rabbit epididymal spermatozoa[J]. Fertility and Sterility,1975,26(12):1257-1265.
[30]Lhuillier P,Rode B,Escalier D,et al. Absence of annulus in human asthenozoospermia:case report[J]. Human Reproduction,2009,24(6):1296-1303.
[31]Tash J S. Protein phosphorylation:the second messenger signal transducer of flagellar motility[J]. Cell Motility and the Cytoskeleton,1989,14(3):332-339.
[32]Suarez S S,Vincenti L,Ceglia M W. Hyperactivated motility induced in mouse sperm by calcium ionophore A23187 is reversible[J]. The Journal of Experimental Zoology,1987,244(2):331-336.
[33]Puga Molina L C,Luque G M,Balestrini P A,et al. Molecular basis of human sperm capacitation[J]. Frontiers In Cell And Developmental Biology,2018,6(6):00072.
[34]Kleinboelting S,Diaz A,Moniot S,et al. Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate[J]. Proceedings of the National Academy of Sciences of the United States of America,2014,111(10):3727-3732.
[35]Teijeiro J M,Marini P E. The effect of oviductal deleted in malignant brain tumor 1 over porcine sperm is mediated by a signal transduction pathway that involves pro-AKAP4 phosphorylation[J]. Reproduction,2012,143(6):773-785.
[36]Visconti P E,Krapf D,Vega-Beltran L L,et al. Ion channels,phosphorylation and mammalian sperm capacitation[J]. Asian Journal of Andrology,2011,13(3):395-405.
[37]Dirami T,Rode B,Jollivet M,et al. Missense mutations in SLC26A8,encoding a sperm-specific activator of CFTR,are associated with human asthenozoospermia[J]. American Journal of Human Genetics,2013,92(5):760-766.
[38]Ho H C,Suarez S S. Characterization of the intracellular calcium store at the base of the sperm flagellum that regulates hyperactivated motility[J]. Biology of Reproduction,2003,68(5):1590-1596.
[39]Tanaka H,Iguchi N,Toyama Y,et al. Mice deficient in the axonemal protein tektin-t exhibit male infertility and Immotile-Cilium syndrome due to impaired inner arm dynein function[J]. Molecular and Cellular Biology,2004,24(18):7958-7964.
[40]Wiesner B,Weiner J,Middendorff R,et al. Cyclic nucleotide-gated channels on the flagellum control Ca2+ entry into sperm[J]. Journal of Cell Biology,1998,142(2):473-484.
[41]Chung J J,Shim S H,Everley R A,et al. Structurally distinct Ca2+ signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility[J]. Cell,2014,157(4):808-822.
[42]Vicente-Carrillo A,Alvarez-Rodriguez M,Rodriguez-Martinez H. The CatSper Channel modulates boar sperm motility during capacitation[J]. Reproductive Biology,2017,17(1):69-78.
[43]Si Y,Olds-Clarke P. Evidence for the involvement of calmodulin in mouse sperm capacitation[J]. Biology of Reproduction,2000,62(5):1231-1239.
[44]Nguyen T M,Combarnous Y,Praud C,et al. Ca2+/Calmodulin-dependent protein kinase kinases(CaMKKs)effects on AMP-Activated protein kinase(AMPK)regulation of chicken sperm functions[J]. PLoS One,2016,11(1):e147559.
[45]Marin-Briggiler C I,Jha K N,Chertihin O,et al. Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation[J]. J Cell Sci,2005,118(Pt 9):2013-2022.
[46]Lopez-Gonzalez I,Vega-Beltran L L,Santi C M,et al. Calmodulin antagonists inhibit T-type Ca2+ currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction[J]. Developmental Biology,2001,236(1):210-219.
[47]Ickowicz D,Finkelstein M,Breitbart H. Mechanism of sperm capacitation and the acrosome reaction:role of protein kinases[J]. Asian Journal of Andrology,2012,14(6):816-821.
[48]Luna C,Colas C,Perez-Pe R,et al. A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep[J]. Biology of Reproduction,2012(93):1-11.
[49]Visconti P E. Understanding the molecular basis of sperm capacitation through kinase design[J]. Proceedings of the National Academy of Sciences of the United States of America,2009,106(3):667-668.
[50]Carrera A,Gerton G L,Moss S B. The major fibrous sheath polypeptide of mouse sperm:structural and functional similarities to the A-kinase anchoring proteins[J]. Developmental Biology,1994,165(1):272-284.
[51]Jha K N,Shivaji S. Identification of the major tyrosine phosphorylated protein of capacitated hamster spermatozoa as a homologue of mammalian sperm a kinase anchoring protein[J]. Molecular Reproduction and Development,2002,61(2):258-270.
[52]Burtan K A,Treash-Osio B,Muller C H,et al. Deletion of type Ⅱ alpha regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization[J]. The Journal of Biological Chemistry,1999,274(34):24131-24136.
[53]Ren D,Navarro B,Perez G,et al. A sperm ion channel required for sperm motility and male fertility[J]. Nature,2001,413(6856):603-609.
[54]Esposito G,Jaiswal B S,Xie F,et al. Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect[J]. Proc Natl Acad Sci U S A,2004,101(9):2993-2998.
[55]Ignotz G G,Suarez S S. Calcium/calmodulin and calmodulin kinase Ⅱ stimulate hyperactivation in demembranated bovine sperm[J]. Biology of Reproduction,2005,73(3):519-526.

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备注/Memo

备注/Memo:
收稿日期:2019-05-08
基金项目:福建省教育厅2017年高等学校创新创业教育改革项目(编号:闽教高[2017]27号试点专业);福建省高校杰出青年科研人才计划(编号:闽教科〔2018〕47号)。
作者简介:吴慧珍(1998—),女,汉族,福建上杭人,研究方向主要是生理生化与信号转导。E-mail:ZAKXWHZ@163.com。
通信作者:谢正露,博士,副教授,研究方向主要是动物生理生化与信号转导。E-mail:xiezhenglu@fafu.edu.cn。
更新日期/Last Update: 2020-05-05