|本期目录/Table of Contents|

[1]徐梦思,黄涛,马亮,等.猪TGFβ1和TGFβRⅠ基因多态性与产活仔数的关联分析[J].江苏农业科学,2016,44(02):38-41.
 Xu Mengsi,et al.Polymorphism of TGFβ1 and TGFβRⅠ and their relationship with number born alive of pigs[J].Jiangsu Agricultural Sciences,2016,44(02):38-41.
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TGFβ1TGFβRⅠ基因多态性
与产活仔数的关联分析
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《江苏农业科学》[ISSN:1002-1302/CN:32-1214/S]

卷:
第44卷
期数:
2016年02期
页码:
38-41
栏目:
生物技术
出版日期:
2016-02-25

文章信息/Info

Title:
Polymorphism of TGFβ1 and TGFβRⅠ and their relationship with number born alive of pigs
作者:
徐梦思 黄涛 马亮 王斌虎 刘丽娟 翟腾蛟 马力鹏
石河子大学动物科技学院,石河子 832000
Author(s):
Xu Mengsiet al
关键词:
TGFβ1基因TGFβRⅠ基因PCR-SSCP产活仔数
Keywords:
-
分类号:
S828.2
DOI:
-
文献标志码:
A
摘要:
为探讨猪转化生长因子β1(TGFβ1)及其受体(TGFβRⅠ)基因多态性与大白猪和长白猪产活仔数的相关性。采用PCR-SSCP方法检测了TGFβ1第6内含子和TGFβRⅠ第7内含子中与猪繁殖力相关的2个突变位点在大白猪和长白猪(共计232头)中的单核苷酸多态性,同时分析多态位点基因型与大白猪和长白猪产活仔数的关联性。结果发现:TGFβ1基因第7外显子上游的第9位碱基存在C→T突变,在大白猪和长白猪中均检出CC和TT 2种基因型,且不同基因型对2猪种产活仔数的影响差异不显著(P>0.05);TGFβRⅠ基因第7内含子第808位碱基存在A→G突变,在大白猪中检出AA、AG、GG 3种基因型,长白猪中未检出GG基因型,大白猪中GG型母猪产活仔数极显著高于AA型(P<0.01),长白猪中,AA型和AG型产活仔数的影响差异不显著(P>0.05)。研究结果表明,TGFβ1基因的突变位点对大白猪和长白猪的产活仔数没有显著影响,TGFβRⅠ基因多态位点与母猪产活仔数显著相关,可作为猪分子遗传育种的候选基因,加快猪育种进程。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2015-03-20
基金项目:国家自然科学基金(编号:30901014、31460586);留学回国人员科研启动基金。
作者简称:徐梦思(1990—),女,新疆石河子人,硕士,主要从事猪分子遗传育种研究。E-mail:1453855240@qq.com。
通信作者:黄涛(1978—),男,湖北武汉人,博士,副教授,主要从事猪分子遗传育种研究。E-mail:taohuang100@sina.com。
更新日期/Last Update: 2016-02-25